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Ansorge, M. S., Zhou, M., Lira, A., Hen, R., & Gingrich, J. A. (2004). Early-life blockade of the 5-HT transporter alters emotional behavior in adult mice. Science (New York, N.Y.)306(5697), 879–881. https://doi.org/10.1126/science.1101678

Bouet, V., Klomp, A., Freret, T., Wylezinska-Arridge, M., Lopez-Tremoleda, J., Dauphin, F., Boulouard, M., Booij, J., Gsell, W., & Reneman, L. (2012). Age-dependent effects of chronic fluoxetine treatment on the serotonergic system one week following treatment. Psychopharmacology221(2), 329–339. https://doi.org/10.1007/s00213-011-2580-1

Brent, D., Emslie, G., Clarke, G., Wagner, K. D., Asarnow, J. R., Keller, M., Vitiello, B., Ritz, L., Iyengar, S., Abebe, K., Birmaher, B., Ryan, N., Kennard, B., Hughes, C., DeBar, L., McCracken, J., Strober, M., Suddath, R., Spirito, A., Leonard, H., … Zelazny, J. (2008). Switching to another SSRI or to venlafaxine with or without cognitive behavioral therapy for adolescents with SSRI-resistant depression: the TORDIA randomized controlled trial. JAMA299(8), 901–913. https://doi.org/10.1001/jama.299.8.901

Brent, D. A., Emslie, G. J., Clarke, G. N., Asarnow, J., Spirito, A., Ritz, L., Vitiello, B., Iyengar, S., Birmaher, B., Ryan, N. D., Zelazny, J., Onorato, M., Kennard, B., Mayes, T. L., Debar, L. L., McCracken, J. T., Strober, M., Suddath, R., Leonard, H., Porta, G., … Keller, M. B. (2009). Predictors of spontaneous and systematically assessed suicidal adverse events in the treatment of SSRI-resistant depression in adolescents (TORDIA) study. The American journal of psychiatry166(4), 418–426. https://doi.org/10.1176/appi.ajp.2008.08070976

Bridge, J. A., Iyengar, S., Salary, C. B., Barbe, R. P., Birmaher, B., Pincus, H. A., Ren, L., & Brent, D. A. (2007). Clinical response and risk for reported suicidal ideation and suicide attempts in pediatric antidepressant treatment: a meta-analysis of randomized controlled trials. JAMA297(15), 1683–1696. https://doi.org/10.1001/jama.297.15.1683

Bridge, J. A., Birmaher, B., Iyengar, S., Barbe, R. P., & Brent, D. A. (2009). Placebo response in randomized controlled trials of antidepressants for pediatric major depressive disorder. The American journal of psychiatry166(1), 42–49. https://doi.org/10.1176/appi.ajp.2008.08020247

Buitelaar, J.K., Keulen, M. van, Nauta, M.H., et al. (2009). De multidisciplinaire richtlijn GGZ Addendum Depressie bij Jeugd. (concept), Utrecht: CBO/Trimbos-instituut.

Carandang, C., Jabbal, R., Macbride, A., & Elbe, D. (2011). A review of escitalopram and citalopram in child and adolescent depression. Journal of the Canadian Academy of Child and Adolescent Psychiatry20(4), 315–324.

Cipriani, A., Zhou, X., Del Giovane, C., et al. (2016). Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis. The Lancet, 388(10047), 881-890. https://doi.org/10.1016/S0140-6736(16)30385-3

Cohen, D., Deniau, E., Maturana, A., Tanguy, M. L., Bodeau, N., Labelle, R., Breton, J. J., & Guile, J. M. (2008). Are child and adolescent responses to placebo higher in major depression than in anxiety disorders? A systematic review of placebo-controlled trials. PloS one3(7), e2632. https://doi.org/10.1371/journal.pone.0002632

Cox, G. R., Fisher, C. A., De Silva, S., Phelan, M., Akinwale, O. P., Simmons, M. B., & Hetrick, S. E. (2012). Interventions for preventing relapse and recurrence of a depressive disorder in children and adolescents. The Cochrane database of systematic reviews11, CD007504. https://doi.org/10.1002/14651858.CD007504.pub2

Curry, J., Silva, S., Rohde, P., Ginsburg, G., Kratochvil, C., Simons, A., Kirchner, J., May, D., Kennard, B., Mayes, T., Feeny, N., Albano, A. M., Lavanier, S., Reinecke, M., Jacobs, R., Becker-Weidman, E., Weller, E., Emslie, G., Walkup, J., Kastelic, E., … March, J. (2011). Recovery and recurrence following treatment for adolescent major depression. Archives of general psychiatry68(3), 263–269. https://doi.org/10.1001/archgenpsychiatry.2010.150

Deacon, G., Kettle, C., Hayes, D., Dennis, C., & Tucci, J. (2017). Omega 3 polyunsaturated fatty acids and the treatment of depression. Critical reviews in food science and nutrition57(1), 212–223. https://doi.org/10.1080/10408398.2013.876959

Dubicka, B.,March, J. et al. (2009). The treatment of Adolescent Major depression: a comparison of the ADAPT and TADS trials. In: Depression in childhood and adolescence: the way forward; ACAMH Occasional Papers, no.28.

Duffy, A., Heffer, N., Goodday, S. M., Weir, A., Patten, S., Malhi, G. S., & Cipriani, A. (2018). Efficacy and tolerability of lithium for the treatment of acute mania in children with bipolar disorder: A systematic review: A report from the ISBD-IGSLi joint task force on lithium treatment. Bipolar disorders20(7), 583–593. https://doi.org/10.1111/bdi.12690

Emslie, G. J., Heiligenstein, J. H., Hoog, S. L., Wagner, K. D., Findling, R. L., McCracken, J. T., Nilsson, M. E., & Jacobson, J. G. (2004). Fluoxetine treatment for prevention of relapse of depression in children and adolescents: a double-blind, placebo-controlled study. Journal of the American Academy of Child and Adolescent Psychiatry43(11), 1397–1405. https://doi.org/10.1097/01.chi.0000140453.89323.57

Emslie, G. J., Kennard, B. D., Mayes, T. L., Nightingale-Teresi, J., Carmody, T., Hughes, C. W., Rush, A. J., Tao, R., & Rintelmann, J. W. (2008). Fluoxetine versus placebo in preventing relapse of major depression in children and adolescents. The American journal of psychiatry165(4), 459–467. https://doi.org/10.1176/appi.ajp.2007.07091453

Emslie, G. J., Mayes, T., Porta, G., Vitiello, B., Clarke, G., Wagner, K. D., Asarnow, J. R., Spirito, A., Birmaher, B., Ryan, N., Kennard, B., DeBar, L., McCracken, J., Strober, M., Onorato, M., Zelazny, J., Keller, M., Iyengar, S., & Brent, D. (2010). Treatment of Resistant Depression in Adolescents (TORDIA): week 24 outcomes. The American journal of psychiatry167(7), 782–791. https://doi.org/10.1176/appi.ajp.2010.09040552

Emslie, G.J., Tao, R., et al. How to use medication to manage depression? In: Rey JM, Birmaher B ,editors. (2009). Treating child and adolescent depression. Philadelphia: Wolters Kluwer/Lippincot, Williams and Wilkins; p 69-86.

Emslie, G. J., Ventura, D., Korotzer, A., & Tourkodimitris, S. (2009). Escitalopram in the treatment of adolescent depression: a randomized placebo-controlled multisite trial. Journal of the American Academy of Child and Adolescent Psychiatry48(7), 721–729. https://doi.org/10.1097/CHI.0b013e3181a2b304

Emslie, G. J., Kennard, B. D., Mayes, T. L., Nakonezny, P. A., Moore, J., Jones, J. M., Foxwell, A. A., & King, J. (2015). Continued Effectiveness of Relapse Prevention Cognitive-Behavioral Therapy Following Fluoxetine Treatment in Youth With Major Depressive Disorder. Journal of the American Academy of Child and Adolescent Psychiatry54(12), 991–998. https://doi.org/10.1016/j.jaac.2015.09.014

Gibbons, R. D., Brown, C. H., Hur, K., Davis, J., & Mann, J. J. (2012). Suicidal thoughts and behavior with antidepressant treatment: reanalysis of the randomized placebo-controlled studies of fluoxetine and venlafaxine. Archives of general psychiatry69(6), 580–587. https://doi.org/10.1001/archgenpsychiatry.2011.2048

Goodyer, I., Dubicka, B., Wilkinson, P., Kelvin, R., Roberts, C., Byford, S., Breen, S., Ford, C., Barrett, B., Leech, A., Rothwell, J., White, L., & Harrington, R. (2007). Selective serotonin reuptake inhibitors (SSRIs) and routine specialist care with and without cognitive behaviour therapy in adolescents with major depression: randomised controlled trial. BMJ (Clinical research ed.)335(7611), 142. https://doi.org/10.1136/bmj.39224.494340.55

Hazell, P., O’Connell, D., Heathcote, D., Robertson, J., & Henry, D. (1995). Efficacy of tricyclic drugs in treating child and adolescent depression: a meta-analysis. BMJ (Clinical research ed.)310(6984), 897–901. https://doi.org/10.1136/bmj.310.6984.897

Hazell P. (2015). Depression in children and adolescents: complementary therapies. BMJ clinical evidence2015, 1008.

Hetrick, S., Merry, S., McKenzie, J., Sindahl, P., & Proctor, M. (2007). Selective serotonin reuptake inhibitors (SSRIs) for depressive disorders in children and adolescents. The Cochrane database of systematic reviews, (3), CD004851. https://doi.org/10.1002/14651858.CD004851.pub2

Homberg, J. R., Olivier, J. D., Blom, T., Arentsen, T., van Brunschot, C., Schipper, P., Korte-Bouws, G., van Luijtelaar, G., & Reneman, L. (2011). Fluoxetine exerts age-dependent effects on behavior and amygdala neuroplasticity in the rat. PloS one6(1), e16646. https://doi.org/10.1371/journal.pone.0016646

Hussain, H., Dubicka, B., Wilkinson, P. (2018). Recent developments in the treatment of major depressive disorder in children and adolescents. Evidence-Based Mental Health, 21(3),101-106.

Ignaszewski, M. J., & Waslick, B. (2018). Update on Randomized Placebo-Controlled Trials in the Past Decade for Treatment of Major Depressive Disorder in Child and Adolescent Patients: A Systematic Review. Journal of child and adolescent psychopharmacology28(10), 668–675. https://doi.org/10.1089/cap.2017.0174

Kennard, B. D., Emslie, G. J., Mayes, T. L., Nightingale-Teresi, J., Nakonezny, P. A., Hughes, J. L., Jones, J. M., Tao, R., Stewart, S. M., & Jarrett, R. B. (2008). Cognitive-behavioral therapy to prevent relapse in pediatric responders to pharmacotherapy for major depressive disorder. Journal of the American Academy of Child and Adolescent Psychiatry47(12), 1395–1404. https://doi.org/10.1097/CHI.0b013e31818914a1

Kennard, B. D., Mayes, T. L., Chahal, Z., Nakonezny, P. A., Moorehead, A., & Emslie, G. J. (2018). Predictors and Moderators of Relapse in Children and Adolescents With Major Depressive Disorder. The Journal of clinical psychiatry79(2), 15m10330. https://doi.org/10.4088/JCP.15m10330

Lin, P. Y., & Su, K. P. (2007). A meta-analytic review of double-blind, placebo-controlled trials of antidepressant efficacy of omega-3 fatty acids. The Journal of clinical psychiatry68(7), 1056–1061. https://doi.org/10.4088/jcp.v68n0712

March, J. S., & Vitiello, B. (2009). Clinical messages from the Treatment for Adolescents With Depression Study (TADS). The American journal of psychiatry166(10), 1118–1123. https://doi.org/10.1176/appi.ajp.2009.08101606

March, J. S., Silva, S., Petrycki, S., Curry, J., Wells, K., Fairbank, J., Burns, B., Domino, M., McNulty, S., Vitiello, B., & Severe, J. (2007). The Treatment for Adolescents With Depression Study (TADS): long-term effectiveness and safety outcomes. Archives of general psychiatry64(10), 1132–1143. https://doi.org/10.1001/archpsyc.64.10.1132

Mocking, R. J., Harmsen, I., Assies, J., Koeter, M. W., Ruhé, H. G., & Schene, A. H. (2016). Meta-analysis and meta-regression of omega-3 polyunsaturated fatty acid supplementation for major depressive disorder. Translational psychiatry6(3), e756. https://doi.org/10.1038/tp.2016.29

National Institute for Health and Clinical Excellence. (2005). Depression in children and young people. Clinical guideline 28. London: NICE.

Nemets, H., Nemets, B., Apter, A., Bracha, Z., & Belmaker, R. H. (2006). Omega-3 treatment of childhood depression: a controlled, double-blind pilot study. The American journal of psychiatry163(6), 1098–1100. https://doi.org/10.1176/ajp.2006.163.6.1098

Osher, Y., Belmaker, R. H., & Nemets, B. (2006). Clinical trials of PUFAs in depression: State of the art. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry7(4), 223–230. https://doi.org/10.1080/15622970600960173

Richtlijncommissie Addendum depressie bij jeugd. (2009). Multidisciplinaire richtlijn Addendum depressie bij jeugd; Trimbos Instituut, Utrecht.

Rohde, P., Silva, S. G., Tonev, S. T., Kennard, B. D., Vitiello, B., Kratochvil, C. J., Reinecke, M. A., Curry, J. F., Simons, A. D., & March, J. S. (2008). Achievement and maintenance of sustained response during the Treatment for Adolescents With Depression Study continuation and maintenance therapy. Archives of general psychiatry65(4), 447–455. https://doi.org/10.1001/archpsyc.65.4.447

Roobol, T.H., Buitelaar, J.K. (2008). Plaats voor SSRI’s bij de behandeling van ernstig depressieve kinderen en pubers. Ned Tijdschr Geneeskd,152, 1710-1712.

Schneeweiss, S., Patrick, A. R., Solomon, D. H., Dormuth, C. R., Miller, M., Mehta, J., Lee, J. C., & Wang, P. S. (2010). Comparative safety of antidepressant agents for children and adolescents regarding suicidal acts. Pediatrics125(5), 876–888. https://doi.org/10.1542/peds.2009-2317

Stone, M., Laughren, T., Jones, M. L., Levenson, M., Holland, P. C., Hughes, A., Hammad, T. A., Temple, R., & Rochester, G. (2009). Risk of suicidality in clinical trials of antidepressants in adults: analysis of proprietary data submitted to US Food and Drug Administration. BMJ (Clinical research ed.)339, b2880. https://doi.org/10.1136/bmj.b2880

Termorshuizen, F., Palmen, S. J., & Heerdink, E. R. (2015). Suicide Behavior Before and After the Start with Antidepressants: A High Persistent Risk in the First Month of Treatment Among the Young. The international journal of neuropsychopharmacology19(2), pyv081. https://doi.org/10.1093/ijnp/pyv081

Tsapakis, E. M., Soldani, F., Tondo, L., & Baldessarini, R. J. (2008). Efficacy of antidepressants in juvenile depression: meta-analysis. The British journal of psychiatry : the journal of mental science193(1), 10–17. https://doi.org/10.1192/bjp.bp.106.031088

Treatment for Adolescents With Depression Study (TADS) Team, March, J., Silva, S., Curry, J., Wells, K., Fairbank, J., Burns, B., Domino, M., Vitiello, B., Severe, J., Riedal, K., Goldman, M., Feeny, N., Findling, R., Stull, S., Baab, S., Weller, E. B., Robbins, M., Weller, R. A., Jessani, N., … Bartoi, M. (2009). The Treatment for Adolescents With Depression Study (TADS): outcomes over 1 year of naturalistic follow-up. The American journal of psychiatry166(10), 1141–1149. https://doi.org/10.1176/appi.ajp.2009.08111620

Vitiello, B., Silva, S. G., Rohde, P., Kratochvil, C. J., Kennard, B. D., Reinecke, M. A., Mayes, T. L., Posner, K., May, D. E., & March, J. S. (2009). Suicidal events in the Treatment for Adolescents With Depression Study (TADS). The Journal of clinical psychiatry70(5), 741–747. https://doi.org/10.4088/jcp.08m04607

Vitiello, B., Emslie, G., Clarke, G., Wagner, K. D., Asarnow, J. R., Keller, M. B., Birmaher, B., Ryan, N. D., Kennard, B., Mayes, T. L., DeBar, L., Lynch, F., Dickerson, J., Strober, M., Suddath, R., McCracken, J. T., Spirito, A., Onorato, M., Zelazny, J., Porta, G., … Brent, D. A. (2011). Long-term outcome of adolescent depression initially resistant to selective serotonin reuptake inhibitor treatment: a follow-up study of the TORDIA sample. The Journal of clinical psychiatry72(3), 388–396. https://doi.org/10.4088/JCP.09m05885blu

Walkup J. T. (2017). Antidepressant Efficacy for Depression in Children and Adolescents: Industry- and NIMH-Funded Studies. The American journal of psychiatry174(5), 430–437. https://doi.org/10.1176/appi.ajp.2017.16091059

Bronnen vóór 2012

Voor de beschikbare evidence tabellen van de literatuur zie pagina 80 t/m 91 van de Multidisciplinaire Richtlijn Depressie bij Jeugd, addendum.

Cohen, D., Paillère-Martinot, M. L., & Basquin, M. (1997). Use of electroconvulsive therapy in adolescents. Convulsive therapy13(1), 25–31.

Dubicka, B., Hadley, S., & Roberts, C. (2006). Suicidal behaviour in youths with depression treated with new-generation antidepressants: meta-analysis. The British journal of psychiatry : the journal of mental science189, 393–398. https://doi.org/10.1192/bjp.bp.105.011833

Emslie G. J. (2009). Understanding placebo response in pediatric depression trials. The American journal of psychiatry166(1), 1–3. https://doi.org/10.1176/appi.ajp.2008.08101541

Emslie, G. J., Heiligenstein, J. H., Wagner, K. D., Hoog, S. L., Ernest, D. E., Brown, E., Nilsson, M., & Jacobson, J. G. (2002). Fluoxetine for acute treatment of depression in children and adolescents: a placebo-controlled, randomized clinical trial. Journal of the American Academy of Child and Adolescent Psychiatry41(10), 1205–1215. https://doi.org/10.1097/00004583-200210000-00010

Kirsch, I., Deacon, B. J., Huedo-Medina, T. B., Scoboria, A., Moore, T. J., & Johnson, B. T. (2008). Initial severity and antidepressant benefits: a meta-analysis of data submitted to the Food and Drug Administration. PLoS medicine5(2), e45. https://doi.org/10.1371/journal.pmed.0050045

March, J., Silva, S., Vitiello, B., & TADS Team (2006). The Treatment for Adolescents with Depression Study (TADS): methods and message at 12 weeks. Journal of the American Academy of Child and Adolescent Psychiatry45(12), 1393–1403. https://doi.org/10.1097/01.chi.0000237709.35637.c0

NICE. (2005). Schizophrenia, Core interventions in the treatment and management of schizophrenia in adults in primary and second care. NICE clinical guideline 82.

Rey, J. M., & Walter, G. (1997). Half a century of ECT use in young people. The American journal of psychiatry154(5), 595–602. https://doi.org/10.1176/ajp.154.5.595

Swedo, S. E., Allen, A. J., Glod, C. A., Clark, C. H., Teicher, M. H., Richter, D., Hoffman, C., Hamburger, S. D., Dow, S., Brown, C., & Rosenthal, N. E. (1997). A controlled trial of light therapy for the treatment of pediatric seasonal affective disorder. Journal of the American Academy of Child and Adolescent Psychiatry36(6), 816–821. https://doi.org/10.1097/00004583-199706000-00019

Tauscher-Wisniewski, S., Nilsson, M., Caldwell, C., Plewes, J., & Allen, A. J. (2007). Meta-analysis of aggression and/or hostility-related events in children and adolescents treated with fluoxetine compared with placebo. Journal of child and adolescent psychopharmacology17(5), 713–718. https://doi.org/10.1089/cap.2006.0138

Usala, T., Clavenna, A., Zuddas, A., & Bonati, M. (2008). Randomised controlled trials of selective serotonin reuptake inhibitors in treating depression in children and adolescents: a systematic review and meta-analysis. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology18(1), 62–73. https://doi.org/10.1016/j.euroneuro.2007.06.001

Wohlfarth TD, van Zwieten BJ, Lekkerkerker FJ, Gispen-de Wied CC, Ruis JR, Elferink AJ, Storosum JG. (2006). Antidepressants use in children and adolescents and the risk of suicide. European Neuropsychopharmacology, 16(2), 79-83. https://doi.org/10.1016/j.euroneuro.2005.10.004

Weersing VR, Brent DA. (2003). Cognitive behavioral therapy for adolescent depression. In: Kazdin AE, Weisz JR, eds. Evidence-based psychotherapies for children and adolescents. New York: Guilford Press: 135-147

Pubmed search

Cipriani, A., Zhou, X., Del Giovane, C., et al. (2016). Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis. Lancet, 388(10047) , 881-890. https://doi.org/10.1016/S0140-6736(16)30385-3
Depression AND children

Ignaszewski, M. J., & Waslick, B. (2018). Update on Randomized Placebo-Controlled Trials in the Past Decade for Treatment of Major Depressive Disorder in Child and Adolescent Patients: A Systematic Review. Journal of child and adolescent psychopharmacology28(10), 668–675. https://doi.org/10.1089/cap.2017.0174
Treatment depression AND children

Deacon, G., Kettle, C., Hayes, D., Dennis, C., & Tucci, J. (2017). Omega 3 polyunsaturated fatty acids and the treatment of depression. Critical reviews in food science and nutrition57(1), 212–223. https://doi.org/10.1080/10408398.2013.876959
Treatment depression AND children

Hussain, H., Dubicka, B., Wilkinson, P. (2018). Recent developments in the treatment of major depressive disorder in children and adolescents. Evidence-Based Mental Health, 21(3), 101-106.
Treatment depression AND children

Hazell P. (2015). Depression in children and adolescents: complementary therapies. BMJ clinical evidence2015, 1008.
Treatment depression AND children

Kennard, B. D., Mayes, T. L., Chahal, Z., Nakonezny, P. A., Moorehead, A., & Emslie, G. J. (2018). Predictors and Moderators of Relapse in Children and Adolescents With Major Depressive Disorder. The Journal of clinical psychiatry79(2), 15m10330. https://doi.org/10.4088/JCP.15m10330
Depression relapse AND children adolescents

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